“The ART, The SCIENCE and The GRACE Behind The Discoveries of Nipah Virus”
By Prof Dr Chua Kaw Bing
International Medical University, Kuala Lumpur and
National Public Health Laboratory, Ministry of Health, Malaysia.
Wednesday, 11th August 2010: 11am
The Auditorium [Map],
Temasek Life Sciences Laboratory,
1 Research Link,
National University of Singapore
About the virus – In 1999 what seemed to be another outbreak of Japanese Encephalitis began spreading through Malaysia. However, the disease was different and was transmissible from pigs to humans and caused approximately 100 human deaths over six months.
This previously unrecorded viral disease and was implicated by laboratory testing in many of cases of febrile encephalitic and respiratory illnesses among workers who had exposure to pigs in Malaysia and Singapore. The virus was isolated by Dr Chua Kaw Ping, of the University Malaya and on 10 Apr 1999 was officially called the Nipah virus, after one of the villages affected by the outbreak – Sungai Nipah in the Malaysian state of Negeri Sembilan. More than 1,100,000 pigs in the affected areas were destroyed to contain the outbreak, representing approximately 40% of the swine population within Malaysia in 1999.
- March 18 – Events, Today in Science History.com.
- Chua K. B. et al., 1999. Fatal encephalitis due to Nipah virus among pig-farmers in Malaysia. Lancelet, 354(9186): 1257-1259.
- Chua K. B., W. J. Bellini, P. A. Rota, B. H. Harcourt, A. Tamin, S. K. Lam et al., 2000. Nipah virus: a recently emergent deadly paramyxovirus. Science, 288: 1432–1435.
- Chua K. B., B. H. Chua & C. W. Wang, 2002. Anthropogenic deforestation, El Niiio and the emergence of Nipah virus in Malaysia. Malaysian Journal of Pathology, 24(1): 15-21.
- “Scientists Search for Human Hand Behind Outbreak of Jungle Virus,” by Peter Fritsch. The Wall Street Journal, Page 1.
- Bunning M., 2001. Nipah virus outbreak in Malaysia, 1998-1999. J. Swine Health Prod., 9(6): 295-299.
- Chua K. B., 2003. Nipah virus outbreak in Malaysia. J. Clinical Virology, 26(3):265-275.